bs-1149R [Primary Antibody]
EDA Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: EDA

Specificity: This will recognize both the membrane bound and the secreted form of Ectodysplasin.

Immunogen Range: 131-230/391


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1896

Swiss Prot: Q92838

Source: KLH conjugated synthetic peptide derived from human of human ED-1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Seems to be involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Isoform 1 binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor XEDAR.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
FCM(1:20-100)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
ICC(1:100-500)

Predicted Molecular Weight: 24/41


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Cow
Pig
Horse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Oya, Shingo, et al. "Inhibition of Toll-like receptor 4 suppresses liver injury induced by biliary obstruction and subsequent intraportal lipopolysaccharide injection." American Journal of Physiology-Gastrointestinal and Liver Physiology 306.3 (2014): G244-G252.Read more>>
  • Ludan Xing. et al. Spatial and Temporal Expression of Ectodysplasin-A Signaling Pathway Members During Mandibular Condylar Development in Postnatal Mice. J HISTOCHEM CYTOCHEM. ;()Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin-embedded Rat Placenta tissue labeled EDA Polyclonal Antibody, Unconjugated (bs-1149R) at 1:200, followed by conjugation to the secondary antibody and DAB staining


Mouse Placenta probed with EDA Polyclonal Antibody (bs-1149R) at 1:300, overnight at 4˚C.