bs-11541R [Primary Antibody]
Calcipressin 1/DSCR 1 Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Calcipressin 1/DSCR 1

Immunogen Range: 101-200/252


Clonality: Polyclonal

Isotype: IgG

Source: KLH conjugated synthetic peptide derived from human Calcipressin 1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

DSCR1 protein influences cardiac and nervous system development (1). DSCR1 is abundant in the brain, heart, and skeletal muscle. Overexpression of DSCR1 may play a role in the pathogenesis of Down syndrome, in particular mental retardation and/or cardiac defects. DSCR1 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Human DSCR1 maps to gene locus 21q22.1-q22.2.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
ICC(1:100-500)

Predicted Molecular Weight: 28


Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Dog
Sheep
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Mengni Bao. et al. N-Acetylcysteine, an ROS Inhibitor, Alleviates the Pathophysiology of Hyperthyroidism-Induced Cardiomyopathy via the ROS/Ca2+ Pathway. BIOMOLECULES. 2022 Sep;12(9):1195Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded human kidney labeled with Anti-Calcipressin 1/DSCR 1 Polyclonal Antibody, Unconjugated (bs-11541R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.