bs-1168R [Primary Antibody]
CCR4 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CCR4

Immunogen Range: 201-300/360


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1233

Swiss Prot: P51679

Source: KLH conjugated synthetic peptide derived from human CCR-4

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 40


Cross Reactive Species: Human
Rat

Predicted Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Ge, L. P., et al. "Integration of nondegradable polystyrene and degradable gelatin in a core–sheath nanofibrous patch for pelvic reconstruction." International Journal of Nanomedicine 2015:10 3193–3201Read more>>
  • Nicolas Pelisch. et al. CCL3 contributes to secondary damage after spinal cord injury. J Neuroinflamm. 2020 Dec;17(1):1-16Read more>>
  • Han, Dongxu. et al. Subacute cadmium exposure modulates Th1 polarization to trigger ER stress-induced porcine hepatocyte apoptosis via regulation of miR-369-TNF axis. 2021 Oct 14Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded rat exfoliated cells tissue labeled with Anti-CCR4 Polyclonal Antibody, Unconjugated (bs-1168R) at 1:200 followed by conjugation to the secondary antibody and DAB staining


Formalin-fixed and paraffin embedded rat cells labeled with Anti-CCR4/CD194 Polyclonal Antibody, Unconjugated (bs-1168R) followed by conjugation to the secondary antibody and DAB staining


Formalin-fixed and paraffin embedded human hepatitides tissue labeled with Anti-CCR4 Polyclonal Antibody, Unconjugated (bs-1168R) at 1:200 followed by conjugation to the secondary antibody and DAB staining