Host: Rabbit

Target Protein: Tetanus Toxin heavy chain

Immunogen Range: 801-900/1315

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 24255210

Swiss Prot: P04958

Source: KLH conjugated synthetic peptide derived from Clostridium tetani E88 Tetanus toxin heavy chain

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage Condition: Store at -20°C for 12 months..

Background: Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.