Target Protein: Tetanus Toxin heavy chain
Immunogen Range: 801-900/1315
Entrez Gene: 24255210
Swiss Prot: P04958
Source: KLH conjugated synthetic peptide derived from Clostridium tetani E88 Tetanus toxin heavy chain
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition: Store at -20°C for 12 months..
Background: Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.
Cross Reactive Species:
(Clostridium tetani E88)
For research use only. Not intended for diagnostic or therapeutic use.