bs-11930R

DATASHEET

Host: Rabbit

Target Protein: PTF1A

Immunogen Range: 165-260/328

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 256297

Swiss Prot: Q7RTS3

Source: KLH conjugated synthetic peptide derived from human PTF1A

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an important role in cerebellar development. Directly regulated by FOXN4 and RORC during retinal development, FOXN4-PTF1A pathway plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)

Predicted Molecular Weight: 35

Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Cow
Pig

For research use only. Not intended for diagnostic or therapeutic use.