bs-12106R [Primary Antibody]
P2RX7 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: P2RX7

Immunogen Range: 115-160/595


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5027

Swiss Prot: Q99572

Source: KLH conjugated synthetic peptide derived from human P2RX7

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
ICC(1:100-500)

Predicted Molecular Weight: 69


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat
Dog
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Peng, Kuang, et al. "P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation." International Journal of Molecular Medicine.Read more>>
  • Zhou, Ying, et al. "P2X7 receptor in spinal tuberculosis: Gene polymorphisms and protein levels in Chinese Han population." Infection, Genetics and Evolution (2017).Read more>>
  • Hui Huang. et al. The potential of the P2X7 receptor as a therapeutic target in a sub-chronic PCP-induced rodent model of schizophrenia. J Chem Neuroanat. 2021 Jun;:101993Read more>>
  • Zhi Lu. et al. Dioscin ameliorates diabetes cognitive dysfunction via adjusting P2X7R/NLRP3 signal. Int Immunopharmacol. 2021 Nov;:108314Read more>>
  • Xue-qi Liu. et al. Blocking ATP-P1Rs axis attenuate alcohol-related liver fibrosis. LIFE SCI. 2023 Jun;:121896Read more>>