bs-1233R-A594 [Conjugated Primary Antibody]
SHP-2/PTPN11 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: SHP-2/PTPN11

Immunogen Range: 501-597/597

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5781

Swiss Prot: Q06124

Source: KLH conjugated synthetic peptide derived from human PTPN11

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage Condition: Store at 4°C for 12 months.

Background: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.

Conjugation: ALEXA FLUOR® 594

Excitation/ Emission: 590nm/617nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Cow
Pig
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Yan et al. Effects of mitochondrial translocation of telomerase on drug resistance in hepatocellular carcinoma cells. (2015) J.Cance. 6:151-9Read more>>
  • Xiangjun Li. et al. Effect of environmental tobacco smoke on COX\2 and SHP\2 expression in a periodontitis rat model. Oral Dis. 2021 Mar;27(2):338-347Read more>>