bs-1233R-Cy3 [Conjugated Primary Antibody]
PTPN11 Polyclonal Antibody, Cy3 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: PTPN11

Immunogen Range: 501-597/597


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5781

Swiss Prot: Q06124

Source: KLH conjugated synthetic peptide derived from human PTPN11

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 68


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Cow
Pig
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Yan et al. Effects of mitochondrial translocation of telomerase on drug resistance in hepatocellular carcinoma cells. (2015) J.Cance. 6:151-9Read more>>
  • Xiangjun Li. et al. Effect of environmental tobacco smoke on COX\2 and SHP\2 expression in a periodontitis rat model. Oral Dis. 2021 Mar;27(2):338-347Read more>>
VALIDATION IMAGES