bs-12347R-PE [Conjugated Primary Antibody]
EDA Polyclonal Antibody, PE Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: EDA/Ectodermal dysplasia protein

Immunogen Range: 101-200/391


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1896

Swiss Prot: Q92838

Source: KLH conjugated synthetic peptide derived from human Ectodysplasin-A, membrane form/secreted form

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Seems to be involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Isoform 1 binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor XEDAR.

Conjugation: PE

Excitation/ Emission: 496,564nm/578nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)

Predicted Molecular Weight: 41


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat
Cow

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Sisto, Margherita, et al. "Downstream activation of NF‐κB in the EDA‐A1/EDAR signalling in Sjögrens syndrome and its regulation by the ubiquitin‐editing enzyme A20." Clinical & Experimental Immunology (2016).Read more>>
  • Sisto et al. Downstream activation of NF-κB in the EDA-A1/EDAR signalling in Sjögren's syndrome and its regulation by the ubiquitin-editing enzyme A20. (2016) Clin.Exp.Immunol. Read more>>
VALIDATION IMAGES