bs-1239R

DATASHEET

Host: Rabbit

Target Protein: MUC1

Immunogen Range: 1051-1255/1255

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4582

Swiss Prot: P15941

Source: KLH conjugated synthetic peptide derived from human MUC1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IHC-P(1:200-400)

Predicted Molecular Weight: 138

Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Dog
Horse

For research use only. Not intended for diagnostic or therapeutic use.