bs-12413R [Primary Antibody]
LTBP1 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: LTBP1

Immunogen Range: 221-320/1721


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4052

Source: KLH conjugated synthetic peptide derived from human LTBP1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Latent transforming growth factor-beta 1 binding protein 1 (LTBP-1), a heavy glycoprotein, is part of the platelet-derived TGF-beta 1 complex. LTBP-1 serves as an anchor for latent TGF-beta in the extracellular matrix and is a component of microfibrillar structures. Cleavage of LTBP results in LTBP-1, which may sequester latent TGF-beta in the extracellular matrix and regulate its activation. LTBP-1 mRNA is enriched in ovarian carcinoma tissues and highly expressed in serous and mucinous adenocarcinomas.

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)

Predicted Molecular Weight: 184


Predicted Cross Reactive Species: Human
Mouse
Rat
Cow
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • William J. Burlingham. et al. Extracellular VesicleCassociated GARP/TGF:LAP Mediates Infectious Allo-tolerance. TRANSPLANT DIRECT. 2023 Jun; 9(6): e1475Read more>>