bs-12423R-PE

DATASHEET

Host: Rabbit

Target Protein: CAPRIN2

Immunogen Range: 101-200/1127

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 65981

Swiss Prot: Q6IMN6

Source: KLH conjugated synthetic peptide derived from human CAPRIN2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Caprin2 is 1127 amino acid highly conserved protein that is ubiquitously expressed with highest levels of expression in brain and spleen. Caprin2 stabilizes cytosolic _-catenin and enhances LEF-1 dependent reporter gene activity as well as the expression of Wnt target genes in mammalian cells. Caprin2 promotes LRP5/6 phosphorylation by GSK-3 and enhances the interaction between Axin and LRP5/6. It is suggested that Caprin2 functions as a proapoptotic inhibitor of the cell cycle. Nine isoforms of Caprin2 exist due to alternative splicing events.

Conjugation: PE

Excitation/ Emission: 496,564nm/578nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 126

Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Sheep
Pig
Horse
Chicken

For research use only. Not intended for diagnostic or therapeutic use.