bs-12431R-A594

DATASHEET

Host: Rabbit

Target Protein: DOCK2

Immunogen Range: 451-550/1830

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1794

Swiss Prot: Q92608

Source: KLH conjugated synthetic peptide derived from human DOCK2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

Conjugation: ALEXA FLUOR® 594

Excitation/ Emission: 590nm/617nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 212

Predicted Cross Reactive Species: Human
Mouse
Rat
Dog
Cow
Sheep

For research use only. Not intended for diagnostic or therapeutic use.