bs-12462R-Cy3 [Conjugated Primary Antibody]
AGPS/Alkyl-DHAP synthase Antibody, Cy3 Conjugated
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]

Host: Rabbit

Target Protein: AGPS/Alkyl-DHAP synthase

Immunogen Range: 31-130/658

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8540

Source: KLH conjugated synthetic peptide derived from human AGPS/Alkyl-DHAP synthase

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage: Store at 4°C for 12 months.

Background: AGPS is a 658 amino acid enzyme that is required for glycerolipid metabolism and ether lipid biosynthesis. Localized to the inner aspect of the peroxisomal membrane, AGPS is likely part of a heterotrimeric complex that is also composed of GNPAT and a modified form of GNPAT. Containing one FAD-binding PCMH-type domain, AGPS utilizes FAD as a cofactor in the synthesis of alkyl-glycerone 3-phophate and a long-chain acid anion from 1-acteyl-glyerone 3-phosphate and a long-chain alcohol. Defects in the gene encoding AGPS results in rhizomelic chondrodysplasia punctata type 3, a disease characterized by vertebral disorders, severe mental retardation, cutaneous lesions, cataracts and rhizomelic shortening of the humerus and femur.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)

Predicted Molecular Weight: 67

Cross Reactive Species: Rat

Predicted Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.