bs-1247R-FITC

DATASHEET

Host: Rabbit

Target Protein: mGluR5

Immunogen Range: 201-300/1204

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 108071

Swiss Prot: Q3UVX5

Source: KLH conjugated synthetic peptide derived from mouse GRM5

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity).

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 132

Cross Reactive Species: Rat

Predicted Cross Reactive Species: Human
Mouse
Dog
Sheep
Chicken

For research use only. Not intended for diagnostic or therapeutic use.