bs-12486R-Cy3

DATASHEET

Host: Rabbit

Target Protein: APC6 Ser560

Modification Site: Ser560

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8881

Source: KLH conjugated synthetic phosphopeptide derived from human APC6 around the phosphorylation site of Ser560

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 72

Predicted Cross Reactive Species: Human
Mouse
Rat
Dog
Cow
Sheep
Pig

For research use only. Not intended for diagnostic or therapeutic use.