DATASHEET
Host:
Rabbit
Target Protein:
E-Selectin/CD62E
Immunogen Range:
501-612/612
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
20339
Swiss Prot:
Q00690
Source:
KLH conjugated synthetic peptide derived from mouse E-Selectin
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
PRODUCT SPECIFIC PUBLICATIONS
- Kong, Lingxi, et al. "The anti-inflammatory effect of kaempferol on early atherosclerosis in high cholesterol fed rabbits." Lipids in Health and Disease 12.1 (2013): 115.Read more>>
- Tu, Q., et al. "Atorvastatin protects against cerebral ischemia/reperfusion injury through anti-inflammatory and antioxidant effects." Neural Regeneration Research 9.3 (2014): 268.Read more>>
- Naito, Chisato, et al. "Facilitatory effects of fetuin-A on atherosclerosis."Atherosclerosis (2016).Read more>>
- Wei, Min Jun, et al. "Identification of OPN, TNC and E-selectin as potential recognition proteins in cerebral vasospasm after subarachnoid hemorrhage."Chinese Neurosurgical Journal 2.1 (2016): 1.Read more>>
- Chou, Kang-Ju, et al. "CD44 Fucosylation on Mesenchymal Stem Cell Enhances Homing and Macrophage Polarization in Ischemic Kidney Injury." Experimental Cell Research (2016).Read more>>
- Zhang, Shengye, et al. "Role of the plasma cascade systems in ischemia/reperfusion injury of bone." Bone (2017).Read more>>
- Zhang, Zhuochao, et al. "Cytokine profiles in Tibetan macaques following α‐1, 3‐galactosyltransferase‐knockout pig liver xenotransplantation." Xenotransplantation (2017).Read more>>
- Zhixiong Li et al. Shuxuening injection facilitates neurofunctional recovery via down-regulation of G-CSF-mediated granulocyte adhesion and diapedesis pathway in a subacute stroke Mousemodel. Biomed Pharmacother. 2020 Jul;127:110213.Read more>>
- Wang X et al. Crosstalk between Akt and NF\B pathway mediates inhibitory effect of gas6 on monocytes\endothelial cells interactions stimulated by P. gingivalis\LPS. J Cell Mol Med. 2020 Jul;24(14):7979-7990.Read more>>
- Chou K et al. Secretome of Hypoxic Endothelial Cells Stimulates Bone Marrow-Derived Mesenchymal Stem Cells to Enhance Alternative Activation of Macrophages. Int J Mol Sci. 2020 Jun 21;21(12):4409.Read more>>
- Qian Liet al. LOX-1 Regulates P. gingivalis-Induced Monocyte Migration and Adhesion to Human Umbilical Vein Endothelial Cells. Front Cell Dev Biol. 2020 Jul 14;8:596.Read more>>
- Na Li. et al. SELE gene as a characteristic prognostic biomarker of colorectal cancer:. J Int Med Res. 2021;49(4)Read more>>
- Wen Xiong. et al. Mechanisms and Molecular Targets of BuShenHuoXue Formula for Osteoarthritis. Acs Omega. 2022;7(5):47034713Read more>>
- Masahiro Terasawa. et al. Anti-Inflammatory Activity of Orally Administered Monostroma nitidum Rhamnan Sulfate against Lipopolysaccharide-Induced Damage to Mouse Organs and Vascular Endothelium. Mar Drugs. 2022 Feb;20(2):121Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded human gastric carcinoma tissue labeled with Anti-E-Selectin Polyclonal Antibody, Unconjugated(bs-1273R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
Formalin-fixed and paraffin embedded human gastric carcinoma tissue labeled with Anti-E-Selectin Polyclonal Antibody, Unconjugated(bs-1273R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
Lane 1: DU145 cell lysates; Lane 2: LoVo cell lysates; probed with E-Selectin/CD62E Polyclonal Antibody, Unconjugated (bs-1273R) at 1:300 overnight at 4˚C. Followed by a conjugated secondary antibody at 1:10000 for 60 min at 37˚C.