bs-1289R [Primary Antibody]
Chrm3 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Chrm3

Immunogen Range: 481-589/589


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 12671

Swiss Prot: Q9ERZ3

Source: KLH conjugated synthetic peptide derived from mouse Chrm3

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 65


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Chen, Bing, et al. "An ENU-Induced Mutation of Nrg1 Causes Dilated Pupils and a Reduction in Muscarinic Receptors in the Sphincter Pupillae." PloS one 6.9 (2011): e25176.Read more>>
  • Zhao, F., et al. "Expression of M3 acetylcholine receptor in asthmatic mice and bronchial airway remodeling prediction." Genet. Mol. Res 15: 3.Read more>>
  • Zhao, Fan, et al. "Expression Imbalance of Cholinergic M2 and M3 Receptors Contributes to the Motility Reduction of the Small Intestine in Spleen Qi Deficiency." Chinese Medicine 5.4 (2014): 165.Read more>>
  • Huang N et al. Chrm3 protects against acinar cell necrosis by stabilizing caspase‐8 expression in severe acute pancreatitis mice model. J Cell Biochem. 2019 Nov 6. Read more>>
  • Tong L et al. Effects of topical pilocarpine on ocular growth and refractive development in rabbits. Eur J Ophthalmol. 2020 Jun 11;1120672120934962.Read more>>
  • Luan Jing. et al. Inhibition of CHRM3 Alleviates Necrosis Via the MAPK-p38/miR-31-5p/RIP3 Axis in l-ArginineCInduced Severe Acute Pancreatitis. Pancreas. 2020 Nov;49(10):1335-1341Read more>>
  • Liyang Tong. et al. Topical bendazol inhibits experimental myopia progression and decreases the ocular accumulation of HIF\1 protein in young rabbits. Ophthal Physl Opt. 2020 Sep;40(5):567-576Read more>>
  • Yan\Hui Wu. et al. Effect of ischemic preconditioning on radiation damage to the submandibular gland in rats. 2021 Mar 3Read more>>
  • Xue Wang. et al. The intact parasympathetic nerve promotes submandibular gland regeneration through ductal cell proliferation. 2021 Jun 07Read more>>
  • Jianchao Ren. et al. Ejaculatory Duct Obstruction Affects Seminal Vesicle Contractile Efficacy and Smooth Muscle Ultrastructure in a Rat Model. ANDROLOGIA. 2023;2023:5022466Read more>>