bs-12996R [Primary Antibody]
Dermcidin/DCD Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Dermcidin/DCD

Immunogen Range: 63-109/110


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 117159

Source: KLH conjugated synthetic peptide derived from human Dermcidin/DCD

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Antimicrobial peptides participate in the innate response, which may provide a barrier for protection against infection. The Dermcidin gene encodes an antimicrobial peptide DCD-1, which is constitutively expressed in sweat glands, secreted into the sweat, and transported to the epidermal surface. DCD-1 displays antimicrobial activity in response to a variety of pathogenic microorganisms. Overexpression of Dermcidin in breast cancers promotes cell growth and survival, and is coupled with a focal copy number gain of its locus on human chromosome 12q13.2.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
FCM(1:20-100)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
ICC(1:100-500)

Predicted Molecular Weight: 11


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

293T cell lysates probed with Anti-Dermcidin/DCD Polyclonal Antibody, Unconjugated (bs-12996R) at 1:300 overnight at 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:5000 for 90 min at 37˚C.\n