bs-13136R-Cy3

DATASHEET

Host: Rabbit

Target Protein: FAM134B

Specificity: There is a chance that this protein will cross-react with MSL2 based on a 73% non-sequential sequence similarity.

Immunogen Range: 210-310/497

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 54463

Swiss Prot: Q9H6L5

Source: KLH conjugated synthetic peptide derived from human FAM134B

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720).

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 55

Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Cow
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.