bs-13196R-Biotin

DATASHEET

Host: Rabbit

Target Protein: FPGS/Folylpolyglutamate synthase

Immunogen Range: 51-150/587

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2356

Source: KLH conjugated synthetic peptide derived from human FPGS/Folylpolyglutamate synthase

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq, Jul 2008].

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 60

Predicted Cross Reactive Species: Human
Mouse
Rat
Dog
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.