bs-13249R-A647

DATASHEET

Host: Rabbit

Target Protein: G protein alpha inhibitor 1

Immunogen Range: 21-120/354

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2770

Source: KLH conjugated synthetic peptide derived from human G protein alpha inhibitor 1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.

Conjugation: ALEXA FLUOR® 647

Excitation/ Emission: 650nm/665nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 40

Predicted Cross Reactive Species: Human
Mouse
Rat
Cow
Sheep
Pig
Zebrafish

For research use only. Not intended for diagnostic or therapeutic use.