bs-1346R-Cy3 [Conjugated Primary Antibody]
Tp73 protein Polyclonal Antibody, Cy3 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Tp73 protein

Immunogen Range: 501-631/631


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 22062

Swiss Prot: Q9JJP2

Source: KLH conjugated synthetic peptide derived from mouse Tp73 protein

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 70


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • YONG, Mei, et al. "Expression and Clinical Implications of P53, P63 and P73 Protein in Malignant."Read more>>
  • Liu, Jianhui, et al. "Silica nanoparticle exposure inducing granulosa cell apoptosis and follicular atresia in female Balb/c mice." Environmental Science and Pollution Research (2017): 1-12.Read more>>
  • Shi et al. Survivin-2B promotes autophagy by accumulating IKK alpha in the nucleus of selenite-treated NB4 cells. (2014) Cell.Death.Di. 5:e1071Read more>>
  • Kejian Shi. et al. ATM/IKK alpha axis regulates the crosstalk between autophagy and apoptosis in selenite-treated Jurkat cells. CHEM-BIOL INTERACT. 2022 Nov;367:110178Read more>>
VALIDATION IMAGES