bs-13695R-Biotin

DATASHEET

Host: Rabbit

Target Protein: PAG1

Immunogen Range: 331-432/432

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 55824

Swiss Prot: Q9NWQ8

Source: KLH conjugated synthetic peptide derived from human PAG1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 47

Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Dog
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.