bs-13752R-Cy7

DATASHEET

Host: Rabbit

Target Protein: Claudin 16

Immunogen Range: 95-150/305

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 10686

Swiss Prot: Q9Y5I7

Source: KLH conjugated synthetic peptide derived from human Claudin 16

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients. Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors.

Conjugation: Cy7

Excitation/ Emission: 743nm/767nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 34

Predicted Cross Reactive Species: Human
Mouse
Rat
Dog
Cow
Sheep
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.