Target Protein: CEP290
Immunogen Range: 131-230/2479
Entrez Gene: 80184
Swiss Prot: O15078
Source: KLH conjugated synthetic peptide derived from human CEP290
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage: Store at 4°C for 12 months.
Background: This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq, Jul 2008
Predicted Molecular Weight: 291
Cross Reactive Species: Mouse
Predicted Cross Reactive Species:
For research use only. Not intended for diagnostic or therapeutic use.