bs-13909R-Cy5

DATASHEET

Host: Rabbit

Target Protein: CHK2 (Thr26)

Modification Site: Thr26

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 11200

Swiss Prot: O96017

Source: KLH conjugated Synthesised phosphopeptide derived from human CHK2 around the phosphorylation site of Thr26

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.

Conjugation: Cy5

Excitation/ Emission: 625,650nm/670nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.