bs-14160R-RBITC [Conjugated Primary Antibody]
CYP4F3 Polyclonal Antibody, RBITC Conjugated
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Host: Rabbit

Target Protein: CYP4F3

Immunogen Range: 51-150/520


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4051

Swiss Prot: Q08477

Source: KLH conjugated synthetic peptide derived from human CYP4F3

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene, CYP4F3, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F8, is approximately 18 kb away. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

Conjugation: RBITC

Excitation/ Emission: 570nm/595nm

Size: 100µL

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 60 kDa


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Jie Wen. et al. OIT3 serves as a novel biomarker of hepatocellular carcinoma by mediating ferroptosis <i>via</i> regulating the arachidonic acid metabolism.. FRONT ONCOL. 2022 Sep;12:977348-977348Read more>>
  • Tang Xiao-Li. et al. Establishment of a neutrophil extracellular trap-related prognostic signature for colorectal cancer liver metastasis and expression validation of CYP4F3. CLIN EXP MED. 2024 Dec;24(1):1-16Read more>>
  • Ziyang Xu. et al. Cytochrome P450 F3 promotes colorectal cancer via inhibiting NRF2-mediated ferroptosis. TRANSL ONCOL. 2024 Oct;48:102077Read more>>