bs-14395R-Cy3

DATASHEET

Host: Rabbit

Target Protein: DNASE1L2

Immunogen Range: 201-299/299

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1775

Swiss Prot: Q92874

Source: KLH conjugated synthetic peptide derived from human DNASE1L2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

DNASE1L2 is a 299 amino acid secreted protein that is expressed in brain tissue and shares sequence similarity with DNase I, suggesting a possibly role in DNA hydrolysis. The gene encoding DNASE1L2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 31

Cross Reactive Species: Rat

Predicted Cross Reactive Species: Human
Mouse
Cow
Sheep
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.