bs-14413R [Primary Antibody]
DPCD Polyclonal Antibody
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Host: Rabbit

Target Protein: DPCD

Immunogen Range: 121-203/203


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 25911

Swiss Prot: Q9BVM2

Source: KLH conjugated synthetic peptide derived from human DPCD

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

DPCD is a 203 amino acid protein that is expressed at higher levels during ciliated cell differentiation, suggesting that DPCD plays a role in the function or formation of ciliated cells. In primary ciliary dyskinesia (PCD), an autosomal recessive disease that is caused by mutations affecting the proper function of cilia, an exon in the DPCD gene is deleted. The phenotype of PCD is variable, though it may include symptoms such as sinus inverse totalis, infertility or otitis media. In severe cases, patients develop end-stage bronchiectasis and require a lung transplantation. DPCD is highly expressed in testis, with weak expression in heart, pancreas and skeletal muscle.

Size: 100µL

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 23 kDa


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: Mouse Liver tissue lysates; Lane 2: Human U87MG cell lysates probed with DPCD Polyclonal Antibody, Unconjugated (bs-14413R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.