bs-14433R-Cy3

DATASHEET

Host: Rabbit

Target Protein: DSU

Immunogen Range: 101-200/214

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 55686

Swiss Prot: Q8N565

Source: KLH conjugated synthetic peptide derived from human DSU

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

The photoreceptor rod cell that is responsible for vision under conditions of low light consists of stacked arrays of disk membranes that make up its outer segment portion. Regulated by complex biochemical mechanisms, the rod outer segment is under constant renewal as new disks form at the base. MREG (melanoregulin), also known as DSU (dilute suppressor protein homolog) or WDT2, is thought to play a role in membrane fusion and in regulating the biogenesis of disk membranes of photoreceptor rods. MREG interacts with RDS (also known as Peripherin-2), a photoreceptor specific tetraspanin protein that is required to maintain normal cell structure during the renewal process of membrane fusion. MREG is 214 amino acids in length, is expressed in photoreceptor cells and and is expressed as two isoforms due to alternative splicing.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 25

Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Dog
Cow
Pig
Horse

For research use only. Not intended for diagnostic or therapeutic use.