bs-14461R [Primary Antibody]
DUSP9 Polyclonal Antibody
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Host: Rabbit

Target Protein: DUSP9

Immunogen Range: 300-350/384


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1852

Swiss Prot: Q99956

Source: KLH conjugated synthetic peptide derived from human DUSP9

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus. [provided by RefSeq, Jul 2008]

Size: 100µL

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 42 kDa


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: Human HepG2 cell lysates; Lane 2: Human Huh7 cell lysates; Lane 3: Human HeLa cell lysates; Lane 4: Human A431 cell lysates probed with DUSP9 Polyclonal Antibody, Unconjugated (bs-14461R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.