bs-1446R-Cy3

DATASHEET

Host: Rabbit

Target Protein: HSP75/TRAP1

Immunogen Range: 501-650/704

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 10131

Swiss Prot: Q12931

Source: KLH conjugated synthetic peptide derived from human HSP75

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 74

Cross Reactive Species: Rat

Predicted Cross Reactive Species: Human
Mouse
Horse
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.