bs-14643R-BF488

DATASHEET

Host: Rabbit

Target Protein: Estrogen Receptor alpha (Ser106)

Modification Site: Ser106

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2099

Swiss Prot: P03372

Source: KLH conjugated Synthesised phosphopeptide derived from human ER alpha around the phosphorylation site of Ser106

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]

Conjugation: AbBy Fluor® 488

Excitation/ Emission: 499nm/519nm

Size: 100ul

Concentration: 1ug/ul

Applications: FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 66

Cross Reactive Species: Human
Rat

Predicted Cross Reactive Species: Mouse
Cow
Pig
Horse

For research use only. Not intended for diagnostic or therapeutic use.