bs-1478R-Biotin [Conjugated Primary Antibody]
PAFR Polyclonal Antibody, Biotin Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: PAFR

Immunogen Range: 231-342/342


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5724

Swiss Prot: P25105

Source: KLH conjugated synthetic peptide derived from human PAFR

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 38


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog
Cow
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Hammond, Jennetta W., Shao-Ming Lu, and Harris A. Gelbard. "Platelet Activating Factor Enhances Synaptic Vesicle Exocytosis Via PKC, Elevated Intracellular Calcium, and Modulation of Synapsin 1 Dynamics and Phosphorylation." Frontiers in cellular neuroscience 9 (2015).Read more>>
  • Fiedler et al. In vivo RNAi screening identifies Pafah1b3 as a target for combination therapy with TKIs in BCR-ABL1                     +                  BCP-ALL. (2018) Blood.Adv. 2:1229-1242Read more>>
  • Jiaqi Jin. et al. Myocardial ischemia-reperfusion injury is probably due to the excessive production of mitochondrial ROS caused by the activation of 5-HT degradation system mediated by PAF receptor. MOL IMMUNOL. 2023 Mar;155:27Read more>>
  • Silvestro Ennio D'Anna. et al. Bacterial load and related innate immune response in the bronchi of rapid decliners with chronic obstructive pulmonary disease. RESP MED. 2023 Aug;215:107297Read more>>
VALIDATION IMAGES