bs-1488R [Primary Antibody]
Bim/BCL2L11 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Bim/BCL2L11

Immunogen Range: 51-150/198


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 10018

Swiss Prot: O43521

Source: KLH conjugated synthetic peptide derived from human of human Bim

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
FCM(1:20-100)
IHC-P(1:200-400)

Predicted Molecular Weight: 22


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat
Dog
Cow
Sheep
Pig
Horse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Shen S et al. Transcription factor early growth response-1 plays an oncogenic role in salivary gland pleomorphic adenoma. Biotechnol Lett. 2019 Nov 30.Read more>>
  • Yuanhui Zhu. et al. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Induced Parkinsons Disease in Mouse: Potential Association between Neurotransmitter Disturbance and Gut Microbiota Dysbiosis. Acs Chem Neurosci. 2020;11(20):3366C3376Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded mouse intestine tissue labeled with Anti BIM/BCL2L11 Polyclonal Antibody, Unconjugated (bs-1488R) at 1:200 followed by conjugation to the secondary antibody and DAB staining