bs-16176R-APC

DATASHEET

Host: Rabbit

Target Protein: FOXR2

Immunogen Range: 51-150/311

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 139628

Swiss Prot: Q6PJQ5

Source: KLH conjugated synthetic peptide derived from human FOXR2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that express proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXR2 (Forkhead box protein R2), also known as FOXN6 (Forkhead box protein N6), is a 311 amino acid nuclear protein that belongs to the FOX family and contains one fork-head DNA-binding domain. Like other members of the FOX family, FOXR2 is not abundantly expressed in normal tissues but is found at very high levels in breast cancer and primary cancer cell lines and is thought to act as a transcription factor. Through chromosomal aberrations such as retroviral integration, gene amplification or translocation, FOXR2 may be involved the development of certain invasive carcinomas.

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100µL

Concentration: 1ug/ul

Applications: IF(ICC)(1:50-200)
IF()

Predicted Molecular Weight: 36 kDa

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.