bs-1619R-FITC [Conjugated Primary Antibody]
Smad1 + Smad5 Polyclonal Antibody, FITC Conjugated
www.biossusa.com
[email protected]
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DATASHEET

Host: Rabbit

Target Protein: Smad1 + Smad5

Immunogen Range: 361-465/465


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4090, 4086

Source: KLH conjugated synthetic peptide derived from human Smad 5

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100ul

Concentration: 1ug/ul

Applications: FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 52


Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Dog
Cow
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Qu et al. MiR-199a-3p suppresses proliferation and invasion of prostate cancer cells by targeting Smad1. (2017) Oncotarge. 8:52465-52473Read more>>
  • Wei et al. Smurf1 inhibits integrin activation by controlling Kindlin-2 ubiquitination and degradation. (2017) J.Cell.Bio. 216:1455-1471Read more>>
VALIDATION IMAGES