Host: Rabbit
Target Protein: HEY1
Immunogen Range: 51-150/304
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 23462
Swiss Prot: Q9Y5J3
Purification: Purified by Protein A.
Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
Size: 100ul
Concentration: 1mg/ml
Applications:
WB()
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(1:100-500)
ICC(1:100-500)
Predicted Molecular Weight: 34
Cross Reactive Species: Rat
Predicted Cross Reactive Species:
Human
Mouse
Dog
Cow
Sheep
Horse
For research use only. Not intended for diagnostic or therapeutic use.