bs-16868R-FITC

DATASHEET

Host: Rabbit

Target Protein: KSR1

Modification Site: Ser404

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8844

Swiss Prot: Q8IVT5

Source: KLH conjugated synthesised phosphopeptide derived from human KSR1 around the phosphorylation site of Ser404

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

KSR1 is a molecular scaffold and positive regulator of the Raf/MEK/ERK phosphorylation cascade. It was initially considered to be a protein kinase acting in the Ras pathway. KSR1 is required for maximal ERK activation induced by growth factors and by some cytotoxic agents. In resting cells, phosphorylated KSR1 is cytoplasmic and in stimulated cells, dephosphorylated KSR1 is membrane associated.

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 102

Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Dog
Pig

For research use only. Not intended for diagnostic or therapeutic use.