bs-16929R-A350

DATASHEET

Host: Rabbit

Target Protein: KCTD17

Immunogen Range: 1-100/521

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 79734

Swiss Prot: Q8N5Z5

Source: KLH conjugated synthetic peptide derived from human KCTD17

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243).

Conjugation: ALEXA FLUOR® 350

Excitation/ Emission: 346nm/442nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 36

Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Cow
Pig

For research use only. Not intended for diagnostic or therapeutic use.