bs-1695R [Primary Antibody]
Decorin Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Decorin

Immunogen Range: 101-200/347


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1634

Swiss Prot: P07585

Source: KLH conjugated synthetic peptide derived from human Decorin

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Decorin is a member of the small, leucine rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF beta. It is believed that decorin also plays a role in the cell cycle of chondrocytes. Also known as: Decorin; Bone proteoglycan II; CSCD; DCN; DCN protein; Dermatan sulphate proteoglycans II; DKFZp686J19238; DSPG 2; DSPG2; PG 40; PG II; PG S2; PG40; PGII; PGS 2; PGS2; Proteoglycan core protein; SLRR1B; Small leucine rich protein 1B.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)

Predicted Molecular Weight: 36


Cross Reactive Species: Human
Rat
Goat
Others

Predicted Cross Reactive Species: Mouse
Cow
Sheep
Pig
Horse
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Bakker, Erik NTP, et al. "Heterogeneity in Arterial Remodeling among Sublines of Spontaneously Hypertensive Rats." PLoS one 9.9 (2014): e107998.Read more>>
  • Peng, J. Y., et al. "Molecular cloning, expression analysis, and function of decorin in goat ovarian granulosa cells." Domestic Animal Endocrinology (2016).Read more>>
  • Li, Guoqing, et al. "Identifying DCN and HSPD1 as Potential Biomarkers in Colon Cancer Using 2D-LC-MS/MS Combined with iTRAQ Technology." Journal of Cancer 8.3 (2017): 479-489.Read more>>
  • Li, Xinxin, et al. "Long-term thermal manipulation in the late incubation period can inhibit breast muscle development by activating endoplasmic reticulum stress in duck (Anasplatyrhynchos domestica)." Journal of thermal biology 70.Pt B (2017): 37.Read more>>
  • Shibata S et al. Immunohistochemical and ultrastructural evaluation of matrix components in mandibularcondylar cartilage in comparison with growth plate cartilage in cartilage calcification insufficient rats. Anat Sci Int. 2019 Jun 14.Read more>>
VALIDATION IMAGES

Lane 1: Human U2os cell lysates; Lane 2: Human Huvec cell lysates probed with Decorin Polyclonal Antibody, Unconjugated (bs-1695R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.