bs-17465R [Primary Antibody]
SHISA6 Polyclonal Antibody
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Host: Rabbit

Target Protein: SHISA6

Immunogen Range: 251-350/500


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 388336

Swiss Prot: Q6ZSJ9

Source: KLH conjugated synthetic peptide derived from human SHISA6

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Involved in maintenance of high-frequency synaptic transmission at hippocampal CA3-CA1 synapses. Regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression. May play a role in self-renewal and differentiation of spermatogonial stem cells by inhibiting canonical Wnt signaling pathway.

Size: 100µL

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)

Predicted Molecular Weight: 53


Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Mouse Hippocampus lysates; Lane 2: Rat Hippocampus lysates probed with SHISA6 Polyclonal Antibody, Unconjugated (bs-17465R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.


Lane 1: Mouse Hippocampus tissue lysates; Lane 2: Mouse Kidney tissue lysates; Lane 3: Rat Hippocampus tissue lysates probed with SHISA6 Polyclonal Antibody, Unconjugated (bs-17465R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.