Host: Rabbit
Target Protein: DUSP1/MKP1
Specificity: This antibody may interact with DUSP4/MKP2
Immunogen Range: 151-250/367
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 1843
Swiss Prot: P28562
Source: KLH conjugated synthetic peptide derived from human DUSP1
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Background:
Conjugation: ALEXA FLUOR® 488
Excitation/ Emission: 490nm/525nm
Size: 100ul
Concentration: 1ug/ul
Applications:
WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
Predicted Molecular Weight: 39
Cross Reactive Species:
Human
Mouse
Rat
Predicted Cross Reactive Species:
Dog
Cow
Chicken
Rabbit
For research use only. Not intended for diagnostic or therapeutic use.
- Tiss, Ali, et al. "MAP kinase phosphatase DUSP1 is overexpressed in human obese and modulated by physical activity." American Journal of Physiology-Endocrinology and Metabolism (2014): ajpendo-00577.Read more>>
- Kato, Hiroyuki, et al. "Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis." Oncotarget (2016).Read more>>
- Kato, Hiroyuki, et al. "Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis." Oncotarget 7.2 (2016): 2009.Read more>>
- Kouam et al. Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity. (2017) Front.Pharmacol. 8:653Read more>>
- Sha J et al. Dexmedetomidine improves acute stress‐induced liver injury in rats by regulating MKP‐1, inhibiting NF‐κB pathway and cell apoptosis. J Cell Physiol. 2019 Aug;234(8):14068-14078.Read more>>
- Sha J et al. Dexmedetomidine attenuates lipopolysaccharide-induced liver oxidative stress and cell apoptosis in rats by increasing GSK-3β/MKP-1/Nrf2 pathway activity via the α2 adrenergic receptor. Toxicol Appl Pharmacol. 2019 Feb 1;364:144-152. Read more>>
- Meng-ke Fan. et al. Siglec-15 Promotes Tumor Progression in Osteosarcoma via DUSP1/MAPK Pathway. Front Oncol. 2021; 11: 710689Read more>>