bs-1926R-HRP [Conjugated Primary Antibody]
UCP-2 Polyclonal Antibody, HRP Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: UCP-2

Immunogen Range: 201-309/309


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 22228

Swiss Prot: P70406

Source: KLH conjugated synthetic peptide derived from Mouse UCP-2 (Mitochondrial intermembrane space domain)

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat (By similarity).

Conjugation: HRP

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 34


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Chuang, Yao-Chung, et al. "Peroxisome proliferator activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status Read more>>
  • Bo, Jinshuang, et al. "Methylglyoxal Impairs Insulin Secretion of Pancreatic β-Cells through Increased Production of ROS and Mitochondrial Dysfunction Mediated by Upregulation of UCP2 and MAPKs." Journal of Diabetes Research(2015).Read more>>
  • Gaochun Zhu. et al. Mitochondrial uncoupling protein 2 is regulated through heterogeneous nuclear ribonucleoprotein K in lead exposure models. J Environ Sci Heal C. 2021;39(1):1-16Read more>>
  • Songsong Jiang. et al. A Comparison Study on the Therapeutic Effect of High Protein Diets Based on Pork Protein versus Soybean Protein on Obese Mice. FOODS. 2022 Jan;11(9):1227Read more>>
  • Tidwell, Tia R.. et al. Metabolic flux analysis of 3D spheroids reveals significant differences in glucose metabolism from matched 2D cultures of colorectal cancer and pancreatic ductal adenocarcinoma cell lines. CANCER METAB. 2022 Dec;10(1):1-16Read more>>
  • Lei Zhao. et al. Polysaccharides From Pogostemon cablin (Blanco) Benth.: Characterization and Antioxidant Activities. FRONT PHARMACOL. 2022; 13: 933669Read more>>
  • Yaning Biao. et al. Wulingsan Alleviates MAFLD by Activating Autophagy via Regulating the AMPK/mTOR/ULK1 Signaling Pathway. CAN J GASTROENTEROL. 2024 Jul;2024(1):9777866Read more>>
VALIDATION IMAGES