bs-20130R [Primary Antibody]
FAIM3 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: FAIM3

Immunogen Range: 51-150/390


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 9214

Swiss Prot: O60667

Source: KLH conjugated synthetic peptide derived from human FAIM3

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
ICC(1:100-500)

Predicted Molecular Weight: 41


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-FAIM3 Polyclonal Antibody, Unconjugated (bs-20130R) at 1:500 followed by conjugation to the secondary antibody and DAB staining.


Formalin-fixed and paraffin embedded human liver carcinoma labeled with Anti-FAIM3 Polyclonal Antibody, Unconjugated (bs-20130R) at 1:500 followed by conjugation to the secondary antibody and DAB staining.