bs-2015R-A594 [Conjugated Primary Antibody]
S100B Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
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DATASHEET

Host: Rabbit

Target Protein: S100B

Immunogen Range: 31-92/92


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6285

Swiss Prot: P04271

Source: KLH conjugated synthetic peptide derived from human S100B

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Conjugation: ALEXA FLUOR® 594

Excitation/ Emission: 590nm/617nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 10


Cross Reactive Species: Rat

Predicted Cross Reactive Species: Human
Mouse
Cow
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhang, Shuai-nan, et al. "Cerebral potential biomarkers discovery and metabolic pathways analysis of α-synucleinopathies and the dual effects of Acanthopanax senticosus Harms on central nervous system through metabolomics analysis." Journal of ethnopharmacology (2015).Read more>>
  • Li et al. Nerve injury-related autoimmunity activation leads to chronic inflammation and chronic neuropathic pain. (2013) Anesthesiolog. 118:416-29Read more>>
  • Martin Selinger. et al. Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors. COMPUT STRUCT BIOTEC. 2022 Jan;20:2759Read more>>
  • Zhu, Yaqiong. et al. Peripheral nerve defects repaired with autogenous vein grafts filled with platelet-rich plasma and active nerve microtissues and evaluated by novel multimodal ultrasound techniques. Biomaterials Research. 2022 Dec;26(1):1-29Read more>>
VALIDATION IMAGES