DATASHEET
Host:
Rabbit
Target Protein:
FGFR1
Immunogen Range:
31-130/822
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
2260
Swiss Prot:
P11362
Source:
KLH conjugated synthetic peptide derived from human FGFR1
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
Receptor for fibroblast growth factors FGF2 and FGF1. Receptor for FGF23 in the presence of KL (By similarity). Promotes mitogenesis in response to fibroblast growth factors. Activates PLCG1.
VALIDATION IMAGES
Paraformaldehyde-fixed, paraffin embedded (human laryngeal carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FGFR1) Polyclonal Antibody, Unconjugated (bs-20226R ) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Lane 1: Human A673 cell Lysates; Lane 2: Human MOLT4 cell Lysates; Lane 3: Human A549 cell Lysates. Probed with FGFR1 polyclonal Antibody, unconjugated (bs-20226R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.