DATASHEET
Host:
Rabbit
Target Protein:
NCX3
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
6547
Source:
KLH conjugated synthetic peptide derived from human NCX3
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Store at -20°C for 12 months.
Background:
SLC8A3 is a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner.
PRODUCT SPECIFIC PUBLICATIONS
- Zhang J et al. TRPV4 Complexes With the Na/Ca 2 Exchanger and IP 3 Receptor 1 to Regulate Local Intracellular Calcium and Tracheal Tension in Mice. Front. Physiol., 06 December 2019.Read more>>
VALIDATION IMAGES
Formalin-fixed and rat brain tissue labeled with Anti-NCX3 Polyclonal Antibody (bs-2057R), Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining
Lane 1: Mouse Heart tissue lysates; Lane 2: Mouse Kidney tissue lysates; Lane 3: Human U251 cell lysates; Lane 4: Human A549 cell lysates probed with NCX3 Polyclonal Antibody, Unconjugated (bs-2057R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.