bs-2123R-A488 [Conjugated Primary Antibody]
Cyp2-j3 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Cyp2-j3

Immunogen Range: 401-502/502


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1573

Swiss Prot: P51589

Source: KLH conjugated synthetic peptide derived from human Cyp2-j3

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.

Conjugation: ALEXA FLUOR® 488

Excitation/ Emission: 490nm/525nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 55


Cross Reactive Species: Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • You et al. Ophiopogonin D maintains Ca2+ homeostasis in rat cardiomyocytes in vitro by upregulating CYP2J3/EETs and suppressing ER stress. (2016) Acta.Pharmacol.Sin. 37:368-81Read more>>
  • Huang X et al. Ophiopogonin D Reduces Myocardial Ischemia-Reperfusion Injury via Upregulating CYP2J3/EETs in Rats.(2018) Cellular Physiology and Biochemistry.49(4):1646-1658.. Read more>>
  • Zhang J et al. EETs/PPARs activation together mediates the preventive effect of naringenin in high glucose-induced cardiomyocyte hypertrophy.(2019)Biomed Pharmacother;Jan;109:1498-1505.Read more>>
  • Wang J et al. Ophiopogonin D Increases SERCA2a Interaction with Phospholamban by Promoting CYP2J3 UpregulationOxid Med Cell Longev.2020 Dec 31;2020:8857906.Read more>>
VALIDATION IMAGES